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The story starts when your protagonist goes to a party. 
Another character is an alchemist who plans to use your protagonist as a scapegoat.

The story starts when your protagonist decides s/he must get justice. 
Another character is a square who wants everything done by the rules. 

The story starts when your protagonist comes out of the closet. 
Another character is someone your protagonist dated who has slandered your protagonist.

The story starts when your protagonist breaks a promise. 
Another character is a mechanic who once hitched a ride with your protagonist. 

The story starts when your protagonist finds the car won't start. 
Another character is a ski instructor who is psychic. 

The story starts when your protagonist admits to a fantasy. 
Another character is a police officer who is trying to escape a bigger enemy.

The story starts when your protagonist is forced into a car at gunpoint. 
Another character is an alien entity who always shuns other people.

The story starts when your protagonist accepts a new job. 
Another character is a painter who is a movie star.

The story starts when your protagonist takes a bet. 
Another character is a student. who is carrying a deadly disease. 

The story starts when your protagonist tells on someone else. 
Another character is a mind reader who has told your protagonist's secret to the press.

The story starts when your protagonist takes a bet. 
Another character is a doorman who has been forging your protagonist's name.

The story starts when your protagonist opens the closet to find clothes that aren't his/hers. 
Another character is a waiter who invents strange machines. 

The story starts when your protagonist stops to help someone in a car accident. 
Another character is royalty. who is trying to hide the truth. 

The story starts when your protagonist cheats on a partner. 
Another character is a foreign diplomat who is power-hungry. 

The story starts when your protagonist goes to a party. 
Another character is an activist who wants your protagonist to go on a road trip.

The story starts when your protagonist finds a gun in a partner's nightstand drawer. 
Another character is a bus driver who thinks s/he is in competition with your protagonist.

The story starts when your protagonist finds an old book on a friend's shelf. 
Another character is an unscrupulous sort who is determined to move in with your protagonist. 

The story starts when your protagonist tries to return a lost object. 
Another character is a janitor who plans to use your protagonist as a scapegoat. 

The story starts when your protagonist comes out of the closet. 
Another character is a deputy who thinks s/he is just doing his/her duty. 

The story starts when your protagonist opens the closet to find clothes that aren't his/hers. 
Another character is a janitor who believes s/he is from another galaxy.